Learn About GLP-1 Weight Loss
Expert guides and resources to help you understand GLP-1 medications, what to expect, and how to achieve the best results.
GLP-1 Medication Comparison
Compare FDA-approved weight loss medications side-by-side. All data sourced from clinical trials and FDA documentation.
| Medication | Brand Names | Monthly Cost | Average Weight Loss | Frequency | FDA Approved |
|---|---|---|---|---|---|
Tirzepatide Dual GIP/GLP-1 receptor agonist | Mounjaro, Zepbound | $550 - $999 | 20% | Once weekly | |
Semaglutide GLP-1 receptor agonist | Ozempic, Wegovy, Rybelsus | $250 - $599 | 15% | Once weekly | |
Compounded Semaglutide GLP-1 receptor agonist (compounded) | Various compounding pharmacies | $199 - $399 | 12% | Once weekly | |
Liraglutide GLP-1 receptor agonist | Saxenda, Victoza | $1200 - $1500 | 8% | Once daily |
Tirzepatide
Tirzepatide is a first-in-class dual GIP/GLP-1 receptor agonist. Approved as Zepbound for weight management in 2023, it has shown superior weight loss results compared to single-action GLP-1 medications.
- Up to 22.5% average weight loss
- Dual-action mechanism
- FDA approved for weight management
Semaglutide
Semaglutide is a GLP-1 receptor agonist FDA-approved for chronic weight management. Originally developed for type 2 diabetes treatment (Ozempic), the higher-dose version (Wegovy) received FDA approval for weight loss in 2021.
- 15-20% average weight loss
- Once-weekly dosing
- FDA approved for chronic weight management
Compounded Semaglutide
Compounded semaglutide is a pharmacy-prepared version of semaglutide available at lower cost. While containing the same active ingredient, it is not FDA-approved and may vary in quality and efficacy between compounding pharmacies.
- Lower cost alternative
- Same active ingredient
- Once-weekly dosing
Important Medical Information
- • All GLP-1 medications require a prescription from a licensed healthcare provider
- • Individual results vary based on dosage, lifestyle factors, and medical history
- • Common side effects include nausea, diarrhea, and constipation, typically mild and temporary
- • Not suitable for people with certain medical conditions including thyroid cancer history
- • Always consult with a healthcare provider before starting any weight loss medication
Latest Articles & Guides
How to Choose a GLP-1 Weight Loss Clinic: A Checklist
Not all weight loss clinics are created equal. Use this evidence-based checklist to evaluate GLP-1 providers and find safe, quality care.
What Happens When You Stop GLP-1 Medications? Weight Regain Data
Clinical data shows significant weight regain after stopping GLP-1 medications. Here is what the STEP 1 extension trial and other studies found.
Telehealth vs In-Person GLP-1 Clinics: How to Choose
Compare telehealth and in-person options for GLP-1 weight loss treatment. Understand the differences in care, cost, convenience, and what to look for.
GLP-1 Insurance Coverage: What You Need to Know
Insurance coverage for GLP-1 weight loss medications is complicated and changing fast. Here is what is covered, what is not, and how to navigate the system.
How Do GLP-1 Medications Work? The Science Explained
Understand the science behind GLP-1 receptor agonists and dual GIP/GLP-1 agonists. How semaglutide and tirzepatide reduce appetite and produce weight loss.
Obesity in America: What the Latest CDC Data Shows
Over 40% of American adults have obesity according to the latest CDC data. Here is what the numbers show and why GLP-1 medications have become so important.
Am I Eligible for GLP-1 Weight Loss Medication? BMI Requirements Explained
Learn the BMI requirements and medical criteria for GLP-1 weight loss medications like Wegovy and Zepbound, based on FDA-approved labeling.
Zepbound (Tirzepatide): Dosing, Cost, and What to Expect
A complete guide to Zepbound for weight loss: FDA approval details, how it differs from Wegovy, dosing, side effects, cost, and clinical trial results.
Wegovy (Semaglutide 2.4 mg): Dosing, Cost, and What to Expect
Everything you need to know about Wegovy for weight loss: FDA approval, dosing schedule, side effects from clinical trials, cost, and eligibility criteria.
Semaglutide and Heart Health: The SELECT Trial Results
The SELECT trial showed semaglutide reduced major cardiovascular events by 20% in people with obesity. Here is what the landmark NEJM study found.
Tirzepatide Clinical Trials: SURMOUNT Results and What They Mean
The SURMOUNT clinical trials showed tirzepatide produced up to 22.5% weight loss. Here is what the data actually showed, with results by dose.
Semaglutide Clinical Trials: STEP Trial Results Explained
A detailed look at the landmark STEP clinical trials that led to FDA approval of Wegovy for weight loss, including actual weight loss percentages and long-term data.
How Much Does Semaglutide Cost? Complete Pricing Guide 2024
Understanding the true cost of semaglutide weight loss treatment. Compare brand name, generic, and compounded options with and without insurance.
GLP-1 Side Effects: What to Expect and How to Manage Them
Understanding GLP-1 medication side effects is key to successful treatment. Learn what to expect and proven strategies to manage common side effects.
Tirzepatide vs Semaglutide: Which GLP-1 is Right for You?
Compare tirzepatide and semaglutide, the two leading GLP-1 medications for weight loss. Understand the differences in effectiveness, side effects, and cost.
What is Semaglutide? A Complete Guide to GLP-1 Weight Loss
Learn everything about semaglutide, the revolutionary GLP-1 medication transforming weight loss treatment. Discover how it works, benefits, side effects, and what to expect.